SFB 852-I: The effect of dietary supplementation of Enterococcus faecium NCIMB 10415 and zinc on signaling gene regulation in the immune response of mesenteric lymph nodes in piglets

Dietary supplementation of probiotics as well as zinc is supposed to improve health in weaning piglets and to protect against infections. Our aim is to identify mechanisms contributing to expected improved defence as result of dietary supplementation. We will examine whole genome gene expression and study signalling pathways in the immune system in mesenteric lymph nodes in piglets untreated or treated with either Enterococcus faecium NCIMB 10415 or zinc. Our data will be analyzed together with data from other projects to find systems biological correlations between all parameters.