Orthogonal Modification of Biopolymers With Variable Peptide Sequences via Ultra-Rapid Covalent Modification

In this project ultra-rapid ambient temperature and catalyst-free coupling chemistry is investigated, to be employed to bind monomer sequence-defined peptides onto poly(saccaride) based surfaces. The aim is to ultimately develop an access route to peptide modified bio-substrates, where the peptide segments constitute functions such as specific cell adhesion, biocidal activity or modulation of crystallization processes.